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Medworm Celiac News
Researchers take aim at digestive disorder
Sun, 03/07/2010 - 20:58Canadian researchers are testing a new drug for patients who suffer from a chronic digestive disorder called celiac disease, which appears to be afflicting a growing number of people. (Source: CTV Health)
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Categories: Celiac News
Small intestinal mucosa expression of putative chaperone fls485
Sat, 03/06/2010 - 18:00Conclusions: Expression and synthesis of fls485 are found in surface lining epithelia of normal human intestinal mucosa and deriving epithelial cell lines. An interdependence of enterocyte differentiation along the crypt-villus axis and fls485 chaperone activity might be possible. (Source: BMC Gastroenterology)
Categories: Celiac News
In Adults With Celiac Disease, Intestinal Damage Doesn't Always Heal
Fri, 03/05/2010 - 10:45When celiac disease is diagnosed in adulthood, mucosal damage might never completely resolve, even on a gluten-free diet, according to a February 9th online report in The American Journal of Gastroenterology. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Categories: Celiac News
New celiac disease-specific quality of life questionnaire developed
Fri, 03/05/2010 - 08:19Researchers have developed a new instrument specifically for measuring quality of life in patients with celiac disease. (Source: MedWire News - Gastroenterology)
Categories: Celiac News
Endocytotic segregation of gliadin peptide 31-49 in enterocytes
Fri, 03/05/2010 - 05:12Conclusions Endocytic segregation of gliadin peptide AA 31–49 seems to be a constitutive process. It explains why this peptide cannot stimulate gluten-sensitive T cells. Presentation of gliadin peptides by HLA-DR proteins via late endosomes within enterocytes might induce a tolerogenic effect and constitutes a potentially promising therapeutic approach for induction of tolerance towards gliadin. (Source: Gut)
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Lysosomal accumulation of gliadin p31-43 peptide induces oxidative stress and tissue transglutaminase-mediated PPAR{gamma} downregulation in intestinal epithelial cells and coeliac mucosa
Fri, 03/05/2010 - 05:12Conclusion p31–43 accumulation in lysosomes leads to epithelial activation via the ROS–TG2 axis. TG2 works as a rheostat of ubiquitination and proteasome degradation and drives inflammation via PPAR downregulation. (Source: Gut)
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Virus infections may be contributing factor in onset of gluten intolerance
Thu, 03/04/2010 - 23:00Recent research findings indicate a possible connection between virus infections, the immune system and the onset of gluten intolerance, also known as celiac disease. (Source: ScienceDaily Headlines)
Categories: Celiac News
Virus infections may be contributing factor in onset of gluten intolerance
Thu, 03/04/2010 - 23:00(Academy of Finland) Recent research findings indicate a possible connection between virus infections, the immune system and the onset of gluten intolerance, also known as celiac disease. (Source: EurekAlert! - Medicine and Health)
Categories: Celiac News
Introducing Gluten During Infection Does Not Increase the Risk of Celiac Disease
Thu, 03/04/2010 - 12:59Introducing gluten to a baby's diet during a period of infection does not increase the risk of celiac disease, Swedish researchers report in the March issue of Pediatrics. Reuters Health Information (Source: Medscape Medical News Headlines)
Categories: Celiac News
Atypical Celiac Disease: Could You Be Missing This Common Problem?
Wed, 03/03/2010 - 06:00For every recognized case of celiac disease, 8 more remain undiagnosed. The reason for this disparity is contingent on the varying presentations of the disease. (Source: Consultant Live)
MedWorm Sponsor Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.
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Diagnostic value of confocal endomicroscopy in celiac disease
Tue, 03/02/2010 - 08:33Endoscopy 2010; 42: 197-202DOI: 10.1055/s-0029-1243937 Improved endoscopic screening with targeted biopsies might enhance diagnostic yield in celiac disease. Confocal endomicroscopy (CEM) allows high-resolution in vivo histological analysis. We compared the endomicroscopic findings during ongoing endoscopy with the histological findings graded according to the Marsh classification.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: Endoscopy)
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Celiac disease is not yet mainstream in endoscopy
Tue, 03/02/2010 - 08:33Endoscopy 2010; 42: 218-219DOI: 10.1055/s-0029-1243903© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Full text (Source: Endoscopy)
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Celiac Disease: Pinpointing Immune System Disturbances
Tue, 03/02/2010 - 06:00New research has identified four aspects of immune system disturbance which lead to the development of coeliac disease. Nearly 40 different inherited risk factors which predispose to the disease have now been identified... (Source: Nutrition/Agriculture News From Medical News Today)
Categories: Celiac News
Celiac Disease: Pinpointing Immune System Disturbances
Tue, 03/02/2010 - 06:00New research has identified four aspects of immune system disturbance which lead to the development of coeliac disease. Nearly 40 different inherited risk factors which predispose to the disease have now been identified. These latest findings could speed the way towards improved diagnostics and treatments for the autoimmune complaint that affects 1 in 100 of the population, and lead to insights into related conditions such as type 1 diabetes... (Source: Health News from Medical News Today)
Categories: Celiac News
13 New Variants Associated With Celiac Disease Risk
Mon, 03/01/2010 - 10:33In a genomewide study, more than half the variants associated with celiac disease correlated with altered activity of nearby genes. Medscape Medical News (Source: Medscape Today Headlines)
MedWorm Sponsor Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.
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Questionnaire-Based Case Finding of Celiac Disease in a Population of 8- to 9-Year-Old Children
Mon, 03/01/2010 - 10:02CONCLUSION: A number of preclinical and low-grade symptomatic patients with CD may be identified by their responses to a mailed questionnaire. (Source: PEDIATRICS)
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Impact of Gluten-free Camp on Quality of Life of Children and Adolescents with Celiac Disease
Mon, 03/01/2010 - 10:02CONCLUSIONS: Children who had CD and attended a week-long gluten-free camp demonstrated improvement in well-being, self-perception, and emotional outlook. The positive effects of camp were more apparent among campers who had been on a GFD for <4 years compared with those who had been on a GFD for ≥4 years, suggesting an adaptation to CD with time. A gluten-free camp that provides an environment of unrestricted foods can at least temporarily alleviate stress and anxiety around food and social interactions. Durability of these observations on return to daily life requires additional study. (Source: PEDIATRICS)
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Infectious Disease and Risk of Later Celiac Disease in Childhood
Mon, 03/01/2010 - 10:02CONCLUSION: These results indicate that parent-reported infection at the time of gluten introduction is not a major risk factor for CD. (Source: PEDIATRICS)
Categories: Celiac News
Celiac Disease Genes Identified In Immune System
Mon, 03/01/2010 - 05:00A UK-led international study has identified four types of genetic disturbance in the immune system that lead to celiac disease, bringing to 40 the total number of known inherited factors that increase a person's risk of developing the disease... (Source: GastroIntestinal News From Medical News Today)
Categories: Celiac News
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